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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2412050Generated: November 3, 2026

1-Methylimidazolidin-2-one → HCID 71252198, compound

https://huagongshe.com/reaction/2412050

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Methylimidazolidin-2-oneHCID 567600—
Reactant(6-Bromopyridin-3-yl)[4-(5-ethyl-3-methylpyridin-2-yl)piperazin-1-yl]methanoneHCID 58484652—
ProductHCID 71252198HCID 7125219876.7%

Reaction Steps

Using (6-bromopyridin-3-yl)[4-(5-ethyl-3-methylpyridin-2-yl)piperazin-1-yl]methanone (389 mg) described in Preparation Example 145 and 1-methylimidazolidin-2-one (120 mg) and by the reaction and treatment in the same manner as in Example 1, the title compound (313 mg) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08816079B2
Source datasetuspto-grants-2014_08
ORD IDord-0de501c9c70b47e9b753e31d5895a5e5
Source noteuspto-grants-2014_08