HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Propanesultam → HCID 71253044, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Propanesultam | HCID 642157 | — |
| Reactant | (4-Bromo-2-fluorophenyl)[4-(5-ethyl-3-methylpyridin-2-yl)piperazin-1-yl]methanone | HCID 58484537 | — |
| Product | HCID 71253044 | HCID 71253044 | 86.5% |
Reaction Steps
Using (4-bromo-2-fluorophenyl)[4-(5-ethyl-3-methylpyridin-2-yl)piperazin-1-yl]methanone (406 mg) described in Preparation Example 211 and isothiazolidine 1,1-dioxide (158 mg) and by the reaction and treatment in the same manner as in Example 262, the title compound (386 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-64153201c7d54e0181cbd28616badf65 |
| Source note | uspto-grants-2014_08 |