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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2412070Generated: November 3, 2026

2-Pyrrolidone → HCID 71252112, compound

https://huagongshe.com/reaction/2412070

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-PyrrolidoneHCID 12025—
Reactant(4-Bromo-2-fluorophenyl)[4-(5-ethyl-3-methylpyridin-2-yl)piperazin-1-yl]methanoneHCID 58484537—
ProductHCID 71252112HCID 71252112—

Reaction Steps

Using (4-bromo-2-fluorophenyl)[4-(5-ethyl-3-methylpyridin-2-yl)piperazin-1-yl]methanone (406 mg) described in Preparation Example 211 and pyrrolidin-2-one (115 μL) and by the reaction and treatment in the same manner as in Example 262, the title compound (350 mg) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08816079B2
Source datasetuspto-grants-2014_08
ORD IDord-047fca8ea9aa49739e7da49e014493f1
Source noteuspto-grants-2014_08