HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Propanesultam → HCID 71252387, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Propanesultam | HCID 642157 | — |
| Reactant | (4-Bromo-2-methylphenyl)[4-(5-ethyl-3-methylpyridin-2-yl)piperazin-1-yl]methanone | HCID 58484569 | — |
| Product | HCID 71252387 | HCID 71252387 | 68.7% |
Reaction Steps
Using (4-bromo-2-methylphenyl) [4-(5-ethyl-3-methylpyridin-2-yl)piperazin-1-yl]methanone (402 mg) described in Preparation Example 253 and isothiazolidine 1,1-dioxide (158 mg) and by the reaction and treatment in the same manner as in Example 262, the title compound (304 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-1d00483e13e34b5bb8001fffe979eb7c |
| Source note | uspto-grants-2014_08 |