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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2412111Generated: November 2, 2026

Methylamine tetrahydrofuran → HCID 71252273, compound

https://huagongshe.com/reaction/2412111

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethylamine tetrahydrofuranHCID 66615946—
ReactantHCID 71252396HCID 71252396—
ProductHCID 71252273HCID 7125227336.1%

Reaction Steps

Using N,N-di-tert-butyloxycarbonyl-2-[4-(5-cyclopropyl-3-methylpyridin-2-yl)piperazine-1-carbonyl]-5-(2-oxopyrrolidin-1-yl)benzamide (70 mg) described in Example 814 and 2 mol/L methylamine tetrahydrofuran solution (216 μL) and by the reaction and treatment in the same manner as in Example 770, the title compound (18 mg) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08816079B2
Source datasetuspto-grants-2014_08
ORD IDord-f1edf5684061446cbcb9e7ffb61b58db
Source noteuspto-grants-2014_08