反应详情

To a suspension of 7 g of 1-phenylsemicarbazide in 100 ml of acetonitrile, cooled down to 0°-5° C., were added 7.4 g of β,β-dichloroacryloyl chloride, under stirring. The addition having been completed, the reaction mixture was stirred at 5° C. for 30 minutes and then at room temperature for 1 (one) hour. The solid that separated was collected by decanting and by filtration, then was washed with diethylether, thus obtaining 8 g of 1-(β,β-dichloroacryloyl)-1-phenyl-semicarbazide, in accordance with the elemental analysis and the I.R. and N.M.R. spectra.

1. temperaturecooled down to 0°-5° C.
2. additionThe addition
3. stirringthe reaction mixture was stirred at 5° C. for 30 minutes
4. customat room temperature
5. customThe solid that separated
6. customwas collected
7. customby decanting and by filtration
8. washwas washed with diethylether