HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanethiol → HCID 178506610, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanethiol | HCID 878 | — |
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | 6-amino-1,3-benzoxazol-2(3H)-one | HCID 826989 | — |
| Reactant | 1H-Imidazole, 4,5-dihydro-2-(methylthio)-, hydriodide (1:1) | HCID 12221228 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 178506610 | HCID 178506610 | — |
Reaction Steps
13 g (86.7 millimols) of the compound obtained in step 3 and 22.2 g of 2-methylthio-2-imidazoline hydroiodide are heated to the reflux temperature in 100 cc of pyridine. The reflux is maintained until the evolution of methanethiol has ceased (about 2-3 hours). When the reaction has ended, the cooled mixture is poured into 1.5 liters of diethyl ether. The gummy residue is washed 3 times with 300 cc of diethyl ether and taken up in 100 cc of ethanol. The product is filtered off and recrystallised from methanol. Its melting point is 270°-272° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04492709 |
| Source dataset | uspto-grants-1985_01 |
| ORD ID | ord-f367bc5c9a7344959305fc245c908dda |
| Source note | uspto-grants-1985_01 |