HCID 20432643, compound → HCID 54553133, compound

HRID 2412437Notes

Reaction equation

HRID 2412437 reaction equation
[CH:1]([N:4]1[C:8]2[CH:9]=[C:10]([C:13](=O)[C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[CH:11]=[CH:12][C:7]=2[N:6]=[C:5]1[NH2:21])([CH3:3])[CH3:2].[CH2:22]([Mg]Br)[CH3:23]>>[CH:1]([N:4]1[C:8]2[CH:9]=[C:10]([C:13]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)=[CH:22][CH3:23])[CH:11]=[CH:12][C:7]=2[N:6]=[C:5]1[NH2:21])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 20432643HCID 20432643, compoundHCID 178418443HCID 178418443, compound

Product 1

HCID 54553133HCID 54553133, compound

Procedure

Following the procedure of Example 69, 1-isopropyl-2-amino-6-benzoylbenzimidazole and ethyl magnesium bromide were reacted to give the title product as both the cis and trans alkylene isomers, M+ =291.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-8e555a1a29fa4177ad6aad3807fcba32
Source dataset
uspto-grants-1985_01
Patent number
US04492708

Reaction notes

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