Water → HCID 13135477, compound

HRID 2412440Notes

Reaction equation

HRID 2412440 reaction equation
[BH4-].[Na+].[CH3:3][CH:4]1[CH:9]([N:10]2[CH:14]=[CH:13][N:12]=[CH:11]2)[C:8](=[O:15])[C:7]2[CH:16]=[CH:17][CH:18]=[CH:19][C:6]=2[O:5]1.O>CO>[CH3:3][CH:4]1[CH:9]([N:10]2[CH:14]=[CH:13][N:12]=[CH:11]2)[CH:8]([OH:15])[C:7]2[CH:16]=[CH:17][CH:18]=[CH:19][C:6]=2[O:5]1

Participants

5

Reactant 3

HCID 962WaterHCID 4311764Sodium borohydrideHCID 13135443HCID 13135443, compound

Product 1

HCID 13135477HCID 13135477, compoundYield 99.1%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

NaBH4 (0.6 g) was added portionwise to a solution of 2-methyl-3-(1-imidazolyl)-2,3-dihydro-4H-1-benzopyran-4 one (1.3 g) in MeOH (70 ml) at room temperature. The mixture, stirred for 2 hours, added with water (300 ml), extracted with CHCl3, dried and evaporated to dryness gave 2-methyl-3-(1-imidazolyl)-2.3-dihydro-4H-1-benzopyran-4-ol (1.3 g); m.p.=160°-175° C.;

Workup

  1. extractionextracted with CHCl3
  2. customdried
  3. customevaporated to dryness

Sources & evidence

ORD record
ord-de6ca0b4a5aa4b2d8a70704aa2d8bee5
Source dataset
uspto-grants-1985_01
Patent number
US04492707

Reaction notes

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