Methanesulfonyl chloride → HCID 20432439, compound

HRID 2412489Notes

Reaction equation

C([NH:4][CH2:5][CH2:6][C:7]1[N:8]=[C:9]([F:31])[N:10]([C:12]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH:11]=1)(=O)C.[CH3:32][S:33](Cl)(=[O:35])=[O:34]>>[F:31][C:9]1[N:10]([C:12]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH:11]=[C:7]([CH2:6][CH2:5][NH:4][S:33]([CH3:32])(=[O:35])=[O:34])[N:8]=1

Participants

Reactant 2

HCID 31297Methanesulfonyl chloride

HCID 20432415HCID 20432415, compound

Product 1

HCID 20432439HCID 20432439, compound

Procedure

Using the same procedure as for the starting material of Example 29 but using methanesulphonyl chloride in place of acetyl chloride, there was obtained 2-fluoro-4-(2-methanesulphonylaminoethyl)-1-triphenylmethylimidazole, which was used without further characterisation.

Sources & evidence

ORD record: ord-7e1ddd9a59cb4c81abc4c58dacb0b701
Source dataset: uspto-grants-1985_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04492692

Reaction notes

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