HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyltriphenylphosphonium iodide → HCID 20432318, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyltriphenylphosphonium iodide | HCID 638159 | — |
| Reactant | Potassium tert-butoxide | HCID 23665647 | — |
| Reactant | 2-Fluoro-1-trityl-1H-imidazole-4-carbaldehyde | HCID 53779028 | — |
| Reactant | HCID 178527699 | HCID 178527699 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 20432318 | HCID 20432318 | — |
Reaction Steps
Methyl triphenylphosphonium iodide was treated with potassium t-butoxide in DMSO. After generation of the phosphorane, 2-fluoro-4-formyl-1-triphenylmethylimidazole was added, and the mixture heated 2 hours at 60°. Extractive work-up and chromatography gave 2-fluoro-1-triphenylmethyl-4-vinylimidazole, having the following n.m.r. in CDCl3 : 5.1 (d, 1H); 5.77 (d, 1H); 6.26-6.63 (m, 1H); 6.48 (s, 1H); 7.1-7.5 (m, 15H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04492692 |
| Source dataset | uspto-grants-1985_01 |
| ORD ID | ord-3526859f8fbd4323b79d6852fceb5d98 |
| Source note | uspto-grants-1985_01 |