Sodium → HCID 20432350, compound

Participants

Reaction Steps

4-(2-Benzoylamino-2-methoxycarbonylvinyl)-2-fluoro-1-triphenylmethylimidazole was hydrogenated in EtOAc using a prehydrogenated sodium--containing platinum oxide catalyst (Adams' catalyst), for 3 days. Removal of catalyst and evaporation gave 4-(2-benzoylamino-2-methoxycarbonylethyl)-2-fluoro-1-triphenylmethylimidazole, having the following n.m.r. in CDCl3 : 3.0 (d, 2H); 3.65 (s, 3H); 4.92 and 5.0 (d of t, 1H); 6.3 (s, 1H); 7.0-7.5 (m, 19H); 7.65-8.0 (m, 2H).

Provenance & Evidence