HCID 54151755, compound → HCID 20432447, compound

Participants

Reaction Steps

4-(2-Benzoylamino-2-methoxycarbonylvinyl)-2-fluoro-1-triphenylmethylimidazole was hydrogenated in EtOAc using prehydrogenated fully active platinum oxide catalyst (Adams' catalyst) for 2.5 days. Work-up gave 4-(2-cyclohexylcarbonylamino-2-methoxycarbonylethyl)-2-fluoro-1-triphenylmethylimidazole, having the following n.m.r. in CDCl3 : 1.0-2.3 (m, 11H); 2.85 (d, 2H); 3.6 (s, 3H); 4.2 and 4.27 (d of t, 1H); 6.24 (s, 1H); 6.8 (d, 1H); 7.0-7.5 (m, 15H).

Provenance & Evidence