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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2412591Generated: October 25, 2026

4-(n-Hexadecanamido)-3-methylbenzoic acid → 2-(n-Pentadecyl)indole-5-carboxylic acid

https://huagongshe.com/reaction/2412591

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(n-Hexadecanamido)-3-methylbenzoic acidHCID 12800009—
ReactantPotassium tert-butoxideHCID 23665647—
Product2-(n-Pentadecyl)indole-5-carboxylic acidHCID 1279721759.9%

Reaction Steps

A mixture of 4-(n-hexadecanamido)-3-methylbenzoic acid (6.3 g) and potassium tert-butoxide (25 g) was treated in a similar manner to that described hereinbefore in Example 1 to give 2-(n-pentadecyl)indole-5-carboxylic acid (3.6 g), in the form of a white solid, m.p. 110°-112° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04493843
Source datasetuspto-grants-1985_01
ORD IDord-d4cb807927ed4c99acdc46c2202aa557
Source noteuspto-grants-1985_01