Hydrochloric Acid → HCID 12799927, compound

Participants

Reaction Steps

A solution of 2-(n-pentadecyl)indole-4-carboxylic acid (15 g) in ethanol (100 ml) containing a solution of hydrogen chloride gas in ethanol (100 ml, of strength 35% w/v) was refluxed for 6 hours. After cooling, the solution was poured into water and the solid was collected and was recrystallised from methanol to give ethyl 2-(n-pentadecyl)indole-4-carboxylate (12.4 g), in the form of a pale yellow solid, m.p. 42°-45° C.

Provenance & Evidence