1,4-Dioxane → HCID 12799930, compound

Participants

Reaction Steps

Raney nickel (5 g) was added to a solution of ethyl 2-(n-pentadecyl)-3-methylthioindole-5-carboxylate (0.5 g) in dioxan (25 ml) and the mixture was heated on a steam bath for 1 hour. The mixture was filtered hot and the filtrate was evaporated in vacuo to give a white solid. This solid was recrystallised from petroleum ether (b.p. 60°-80° C.) to give ethyl 2-(n-pentadecyl)indole-5-carboxylate (0.35 g), m.p. 89°-91° C.

Provenance & Evidence