5-Bromothiophene-2-carbaldehyde → HCID 53737529, compound

HRID 2412657Notes

Reaction equation

HRID 2412657 reaction equation
[NH2:1][CH2:2][P:3](=[O:10])([O:7][CH2:8][CH3:9])[O:4][CH2:5][CH3:6].[Br:11][C:12]1[S:16][C:15](C=O)=[CH:14][CH:13]=1>>[Br:11][C:12]1[S:16][C:15](=[N:1][CH2:2][P:3](=[O:10])([O:7][CH2:8][CH3:9])[O:4][CH2:5][CH3:6])[CH2:14][CH:13]=1

Participants

3

Reactant 2

HCID 784285-Bromothiophene-2-carbaldehydeHCID 1596920Diethyl (aminomethyl)phosphonate

Product 1

HCID 53737529HCID 53737529, compoundYield 100%

Procedure

Starting from 16.7 g. (0.1 mol) diethyl aminomethylphosphonate and 19.1 g. (0.1 mol) 5-bromothien-2-aldehyde and following a procedure identical to that described in Example 1, 34 g. (yield: 100%) of the desired product are obtained in the form of a yellow oil.

Sources & evidence

ORD record
ord-06ea6ab4cf0f444cb4e24d7aa4d3a1ce
Source dataset
uspto-grants-1985_01
Patent number
US04493931

Reaction notes

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