O-Allylhydroxylamine hydrochloride → 2-Allyloxyimino-2-(3-hydroxyphenyl)acetic acid

HRID 2412698Notes

Reaction equation

HRID 2412698 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([C:8](=O)[C:9]([OH:11])=[O:10])[CH:5]=[CH:6][CH:7]=1.Cl.[CH2:14]([O:17][NH2:18])[CH:15]=[CH2:16]>>[CH2:14]([O:17][N:18]=[C:8]([C:4]1[CH:5]=[CH:6][CH:7]=[C:2]([OH:1])[CH:3]=1)[C:9]([OH:11])=[O:10])[CH:15]=[CH2:16]

Participants

3

Reactant 2

HCID 3084724O-Allylhydroxylamine hydrochlorideHCID 135480972-(3-Hydroxyphenyl)-2-oxo-ethanoic acid

Product 1

HCID 538422242-Allyloxyimino-2-(3-hydroxyphenyl)acetic acidYield 101.4%

Procedure

2-(3-Hydroxyphenyl)glyoxylic acid (2.0 g.) and O-allylhydroxylamine hydrochloride (1.7 g.) were reacted according to a similar manner to that of Preparation 5-(2)(a) to give oil of 2-allyloxyimino-2-(3-hydroxyphenyl)acetic acid (syn isomer) (2.7 g.).

Workup

  1. customof Preparation 5-(2)(a)

Sources & evidence

ORD record
ord-55b8cc4058054ec5a3f18549c28f1f6a
Source dataset
uspto-grants-1985_01
Patent number
US04493833

Reaction notes

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