Methyl iodide → HCID 13199806, compound

HRID 2412855Notes

Reaction equation

HRID 2412855 reaction equation
[Cl:1][C:2]1[C:7]([NH2:8])=[CH:6][CH:5]=[CH:4][N:3]=1.[CH3:9][I:10]>C(O)C>[I-:10].[CH3:9][N+:3]1[CH:4]=[CH:5][CH:6]=[C:7]([NH2:8])[C:2]=1[Cl:1]

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 805282-Chloro-3-pyridylamine

Product 1

HCID 13199806HCID 13199806, compoundYield 57.6%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 2-chloro-3-aminopyridine (12.8 g) and methyl iodide (56.8 g) was allowed to stand overnight in dark place at room temperature. To the mixture was added ethanol (20 ml) and the precipitates were collected by filtration, washed with diisopropyl ether and dried to give 1-methyl-2-chloro-3-aminopyridinium iodide (15.5 g), mp. 165° to 167° C. (dec.).

Workup

  1. filtrationthe precipitates were collected by filtration
  2. washwashed with diisopropyl ether
  3. customdried

Sources & evidence

ORD record
ord-dfb4a9172b5f4b60972e2807e75fe127
Source dataset
uspto-grants-1985_01
Patent number
US04495182

Reaction notes

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