Hydrochloric Acid → HCID 20431321, compound

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Equimolar amounts of 2-amino-6-chloropurine, 4-bromoethyl-1,3-dioxane (prepared according to Price C. C. J. Amer. Chem. Soc. 1950, 72, 5335-6) and anhydrous potassium carbonate were mixed in dry dimethyl formamide. After stirring for seven days at room temperature the mixture was filtered and the filtrate evaporated at reduced pressure. The residue was triturated with hot ethanol and undissolved material filtered off. The filtrate was evaporated to dryness and a yellow crystalline solid was obtained which was recrystallized from chloroform to give colourless rod-shaped crystalls. M.p. 169°-70° C. (uncorr.) UV Spectra (hydrochloric acid 0.01 mol/l): λmax (nm) 308, 245. UV spectra (ethanol): λmax (nm) 310, 247. M.S.: 11.2 a J., m/e (int): 271/269 (0.19/0.55), 226/224 (0.11/0.28) 212/210 (0.38/0.82) 171/169 (0.35/1.0)

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