HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylamine → 4-Dimethylamino-[1,2,4]triazolo[4,3-a]quinoxaline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | 4-Chloro[1,2,4]triazolo[4,3-a]quinoxaline | HCID 1126118 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 4-Dimethylamino-[1,2,4]triazolo[4,3-a]quinoxaline | HCID 6622993 | 44% |
Reaction Steps
A slurry of 2.0 g. (0.01 mole) of 4-chloro-[1,2,4]triazolo[4,3-a]quinoxaline (the product of Example 2) in N,N-dimethylformamide (30 ml.) was saturated with dimethylamine gas and stirred at room temperature overnight. The mixture was poured over ice and the precipitate was removed by filtration. Recrystallization from ethanol gave 640 mg. (44% yield) of 4-dimethylamino-[1,2,4]triazolo[4,3-a]quinoxaline, m.p. 184°-186° C. Mass spectrum: m/e, 213 (P).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04495187 |
| Source dataset | uspto-grants-1985_01 |
| ORD ID | ord-b200198c8ec0498091956f11ba361478 |
| Source note | uspto-grants-1985_01 |