反应详情

A mixture of 2.9 g (0.01 mole) of 2,3-bis(4-chlorophenyl)-1H-pyrrole and 2.5 g (0.011 mole) of hexafluoroacetone trihydrate in 50 ml toluene was heated at reflux overnight. The mixture was concentrated on a rotary evaporation and the solid residue was chromatographed on 200 g silica gel (eluting with toluene), then recrystallized from hexane to give 3.8 g of product, m.p. 144°-145° C.

1. temperaturewas heated
2. temperatureat reflux overnight
3. concentrationThe mixture was concentrated on a rotary evaporation
4. customthe solid residue was chromatographed on 200 g silica gel (eluting with toluene)
5. customrecrystallized from hexane