Cyclopropylamine → HCID 13370636, compound

HRID 2412957Notes

Reaction equation

HRID 2412957 reaction equation
[CH:1]1([NH2:4])[CH2:3][CH2:2]1.[O:5]1[CH2:32][CH:6]1[CH2:7][O:8][C:9]1[CH:18]=[C:17]2[C:12]([C:13](=[O:31])[C:14]([C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=3)=[C:15]([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[O:16]2)=[CH:11][CH:10]=1>>[CH:1]1([NH:4][CH2:32][CH:6]([OH:5])[CH2:7][O:8][C:9]2[CH:18]=[C:17]3[C:12]([C:13](=[O:31])[C:14]([C:25]4[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=4)=[C:15]([C:19]4[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=4)[O:16]3)=[CH:11][CH:10]=2)[CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 69828CyclopropylamineHCID 13370622HCID 13370622, compound

Product 1

HCID 13370636HCID 13370636, compoundYield 25%

Procedure

The amine was prepared according to Method B from cyclopropylamine and 7-(2,3-epoxypropoxy)-2,3-diphenylchromone and purified by high pressure liquid chromatography to give white crystals, m.p. 135°-137° (MeOH-ether), in 25% yield.

Workup

  1. custompurified by high pressure liquid chromatography

Sources & evidence

ORD record
ord-d1bb9abf12d24957b830bca0587af759
Source dataset
uspto-grants-1985_01
Patent number
US04495198

Reaction notes

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