HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(tert-Butyloxycarbonyl)-D-methionine → methyl Boc-D-methionyl-glycinate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(tert-Butyloxycarbonyl)-D-methionine | HCID 111051 | — |
| Reactant | Glycine methyl ester hydrochloride | HCID 122755 | — |
| Product | methyl Boc-D-methionyl-glycinate | HCID 13216971 | — |
Reaction Steps
The title compound was prepared by the general method of Example 1 using 24.9 g (0.1 mole) of t-butoxycarbonyl-D-methionine (BOC-D-Met) and 13.8 g (0.11 mole) of glycine methyl ester hydrochloride. The crude product was recrystallized from ethyl acetate/Skellysolve B to give the title compound, which was used in subsequent reactions without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04495178 |
| Source dataset | uspto-grants-1985_01 |
| ORD ID | ord-1af6d6869212431e8f3d0d740c244a36 |
| Source note | uspto-grants-1985_01 |