Morpholine → HCID 20429841, compound

HRID 2413095Notes

Reaction equation

HRID 2413095 reaction equation
Cl[C:2]([CH3:26])([CH3:25])[C:3]([C:5]1[CH:24]=[CH:23][C:8]([C:9]([C:11]2[CH:16]=[CH:15][C:14]([C:17](=[O:22])[C:18]([CH3:21])(Cl)[CH3:19])=[CH:13][CH:12]=2)=[O:10])=[CH:7][CH:6]=1)=[O:4].[NH:27]1[CH2:32][CH2:31][O:30][CH2:29][CH2:28]1>>[O:30]1[CH2:31][CH2:32][N:27]([C:2]([CH3:26])([CH3:25])[C:3]([C:5]2[CH:24]=[CH:23][C:8]([C:9]([C:11]3[CH:16]=[CH:15][C:14]([C:17](=[O:22])[C:18]([CH3:21])([N:27]4[CH2:32][CH2:31][O:30][CH2:29][CH2:28]4)[CH3:19])=[CH:13][CH:12]=3)=[O:10])=[CH:7][CH:6]=2)=[O:4])[CH2:28][CH2:29]1

Participants

3

Reactant 2

HCID 8083MorpholineHCID 20429921HCID 20429921, compound

Product 1

HCID 20429841HCID 20429841, compound

Procedure

78 g of 4,4'-bis-(2-chloro-2-methyl-propanoyl)benzophenone is boiled with 250 ml of morpholine for 15 hours. The excess morpholine is then distilled off under reduced pressure and the residue is crystallized from ethanol. 4,4'-bis-(2-Morpholino-2-methyl-propanoyl)-benzophenone is obtained; m.p. 145°-147°.

Workup

  1. distillationThe excess morpholine is then distilled off under reduced pressure
  2. customthe residue is crystallized from ethanol

Sources & evidence

ORD record
ord-3265ca2efa704ce6b9255b9c01027130
Source dataset
uspto-grants-1985_01
Patent number
US04496447

Reaction notes

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