HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-[(Phenylmethoxy)carbonyl]-L-isoleucine → Ethyl N-Carbobenzyloxy-L-isoleucyl-N-(3-pyridyl)glycinate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-[(Phenylmethoxy)carbonyl]-L-isoleucine | HCID 2724772 | — |
| Reactant | ethyl N-(3-pyridyl)-glycinate | HCID 20255549 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Ethyl N-Carbobenzyloxy-L-isoleucyl-N-(3-pyridyl)glycinate | HCID 54257317 | — |
Reaction Steps
A methylene chloride solution of N-carbobenzyloxy-L-isoleucine and ethyl N-(3-pyridyl)-glycinate was treated with N,N-dicyclohexylcarbodiimide as in example 5A. Purification of the product was accomplished by chromatography on silica-gel.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04496542 |
| Source dataset | uspto-grants-1985_01 |
| ORD ID | ord-d5661415b78f4564b03fe4fd0211cd80 |
| Source note | uspto-grants-1985_01 |