p-Toluenesulfonate → Thieno[2,3-c]pyridin-4-ol

HRID 2413128Notes

Reaction equation

[S:1]([C:5]1[CH:11]=CC(C)=CC=1)([O-])(=O)=O.O=C1[CH2:18][N:17](S(C2C=CC(C)=CC=2)(=O)=O)[CH2:16][C:15]2C=CSC1=2.[CH2:32]([OH:34])[CH3:33].C1CCCCC1>>[OH:34][C:32]1[CH:18]=[N:17][CH:16]=[C:15]2[S:1][CH:5]=[CH:11][C:33]=12

Participants

Reactant 3

HCID 85570p-Toluenesulfonate

HCID 12751998HCID 12751998, compound

HCID 21585052HCID 21585052, compound

Product 1

HCID 13019694Thieno[2,3-c]pyridin-4-olYield 78%

Procedure

This compound is prepared according to the procedure of Example 1(c), from the tosylate described in (b) above (Yield: 78%). White crystals; M.p.=206° C. (ethanol-cyclohexane).

Workup

customThis compound is prepared

Sources & evidence

ORD record: ord-0b60415d113547c79f0fbde34d41ea69
Source dataset: uspto-grants-1985_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04496568

Reaction notes

Loading…