Hydrochloric Acid → HCID 19786398, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 7.0 g of 1-chloro-4-cyanoisoquinoline, 4.3 g of ammonium chloride, 5.3 g of sodium azide and 100 ml of dimethylformamide was heated at 120° C. for 16 hours. The mixture was poured into 600 ml of water and acidified to a pH of 2 with hydrochloric acid. The cream colored precipitate which formed was separated by filtration and dried and then recrystallized from dimethylsulfoxide to give 5-(1H-tetrazol-5-yl)tetrazolo[5,1-a[isoquinoline hemihydrate melting at about 235°-250° C. decomposition.

Provenance & Evidence