Diethyl Ether → HCID 13146233, compound

Participants

Reaction Steps

To a solution of 2.1 g of caproic acid in 50 ml of anhydrous pyridine, while being cooled in ice, was added 4.4 g of DCC. After stirring for 30 minutes, 5.0 g of 6-amidino-2-naphthol methanesulfonate was added to the mixture and further stirred overnight at room temperature. The precipitate formed upon addition of ethyl ether to the reaction mixture was collected by filtration, washed with ethyl ether, dissolved in methanol at room temperature, and filtered to remove the insolubles. The filtrate was concentrated under reduced pressure and the residue was recrystallized from an ethanol-ether mixture to obtain 2.1 g of 6-amidino-2-naphthyl caproate methanesulfonate.

Provenance & Evidence