Stearic Acid → HCID 13146241, compound

Participants

Reaction Steps

To a solution of 5.0 g of stearic acid in 70 ml of anhydrous pyridine, while being cooled in ice, was added 4.4 g of DCC. After stirring for 30 minutes, 5.0 g of 6-amidino-2-naphthol methanesulfonate was added to the mixture and further stirred overnight at room temperature. The precipitate was collected by filtration, washed successively with a small volume of pyridine, ethyl ether, and acetone, dissolved in a dimethylformamide-methanol mixture, and filtered to remove the insolubles. The crystals formed upon addition of ethyl ether to the filtrate were collected by filtration, washed with ethanol, and recrystallized from a dimethylformamide-methanol mixture to obtain 3.3 g of a white to pale brown powder of 6-amidino-2-naphthyl stearate methanesulfonate.

Provenance & Evidence