Methanesulfonic Acid → HCID 13146258, compound

Participants

Reaction Steps

To 40 ml of anhydrous dimethylformamide, were added 4.2 g of 6-amidino-2-naphthyl ε-benzyloxycarbonylaminocaproate methanesulfonate, 1.0 g of methanesulfonic acid, and 0.2 g of 10% palladium-carbon. Hydrogen was passed for 4 hours through the vigorously stirred mixture. After removing the palladium-carbon by filtration, the filtrate was poured into stirred ethyl ether. An oily substance which separated out was washed with ethyl ether and recrystallized from ethanol to obtain 0.87 g of white crystals of 6-amidino-2-naphthyl ε-aminocaproate dimethanesulfonate.

Provenance & Evidence