2,5-Dichlorobenzoic acid → 5-Chloro-2-(4-methoxyphenylamino)benzoic acid

HRID 2413272Notes

Reaction equation

HRID 2413272 reaction equation
Cl[C:2]1[CH:10]=[CH:9][C:8]([Cl:11])=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].[CH3:12][O:13][C:14]1[CH:20]=[CH:19][C:17]([NH2:18])=[CH:16][CH:15]=1>>[Cl:11][C:8]1[CH:9]=[CH:10][C:2]([NH:18][C:17]2[CH:19]=[CH:20][C:14]([O:13][CH3:12])=[CH:15][CH:16]=2)=[C:3]([CH:7]=1)[C:4]([OH:6])=[O:5]

Participants

3

Reactant 2

HCID 57842,5-Dichlorobenzoic acidHCID 7732P-Anisidine

Product 1

HCID 133714805-Chloro-2-(4-methoxyphenylamino)benzoic acid

Procedure

5-Chloro-2-(4-methoxyphenylamino)benzoic acid [X; R=5-Cl, OR°=4-OCH3, R"=H] was prepared from 2,5-dichlorobenzoic acid and p-methoxyaniline according to the procedure of Example 1A, part (a), and obtained as a light green solid, m.p. 188°-189° C.

Workup

  1. customobtained as a light green solid, m.p. 188°-189° C.

Sources & evidence

ORD record
ord-634de06bec33430ea19c4f9da4e585a1
Source dataset
uspto-grants-1985_01
Patent number
US04496590

Reaction notes

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