Hydroxyamine hydrochloride → HCID 73181603, compound

Participants

Reaction Steps

To 50 g of 2-chloro-6,7-dimethoxy-3-quinolinecarboxaldehyde was added 50 g of hydroxylamine hydrochloride in 500 ml of pyridine. The mixture was stirred at room temperature for 16 hours and the solvent was then evaporated to leave a semi-solid material. This was washed with water, filtered and recrystallized from dimethylformamide to give 2-chloro-6,7-dimethoxy-3-quinolinecarboxaldehyde oxime melting at about 237°-237.5° C. with decomposition.

Provenance & Evidence