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HRID2413385

反应详情

EQUATION

反应方程式

HRID 2413385 的结构方程式

REACTANTS

反应物

1
结构：CCCOC(=O)[C@@H]1[C@H](C(=O)OCCC)N(Cc2ccccc2)C(=O)N1Cc1ccccc1
HCID18595938

未命名化合物

PRODUCTS

生成物

1
结构：CCCOC(=O)[C@H]1[C@@H](C(=O)O)N(Cc2ccccc2)C(=O)N1Cc1ccccc1
HCID13276243

未命名化合物

收率 90.7%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：O=P([O-])([O-])[O-]
溶剂HCID1061

Phosphate

O4P-3

PROCEDURE

实验过程

A suspension of di-n-propyl cis-1,3-dibenzyl-2-oxoimidazolidine-4,5-dicarboxylate (200 mg) in 0.1m phosphate buffer (pH 8.0, 20 ml) was treated with Pig Liver Esterase (manufactured by Sigma Lab., 640 units, 4 mg) in a manner similar to that in Example 1 (1) to give (4S,5R)-1,3-dibenzyl-5-n-propoxycarbonyl-2-oxoimidazolidine-4-carboxylic acid (164 mg). M.P., 75°-90° C. [α]D20 =+2.1° (c=1, CHCl3).