HCID 86739899, compound → HCID 86739898, compound

Participants

Reaction Steps

2-Benzhydryloxycarbonyl-7-(3,4-dichlorophenylthio)-acetamido-8-oxo-3-(2-tritylaminoacetamido-thiazol-5-yl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene (1.61 g) is treated with formic acid (30 cc) and distilled water (3 cc) at 50° C. for 30 minutes and then concentrated to dryness under reduced pressure (2 mm Hg; 0.27 kPa) at 40° C. The residue is treated in accordance with the working method described in Example 24, to give 2-carboxy-7-(3,4-dichlorophenylthio)-acetamido-3-(2-glycylamino-thiazol-5-yl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene (0.46 g) in the form of a yellow powder.

Provenance & Evidence