Sodium Methoxide → HCID 54496620, compound

HRID 2413449Notes

Reaction equation

HRID 2413449 reaction equation
C[O-].[Na+].[Cl:4][C:5]1[CH:6]=[N:7][C:8]2[C:13]([CH:14]=1)=[CH:12][CH:11]=[C:10]([Cl:15])[C:9]=2[CH:16]=O>CO.C(O)C>[Cl:4][C:5]1[CH:6]=[N:7][C:8]2[C:13]([CH:14]=1)=[CH:12][CH:11]=[C:10]([Cl:15])[C:9]=2[CH:16]=[CH:16][C:9]1[C:10]([Cl:15])=[CH:11][CH:12]=[C:13]2[C:8]=1[N:7]=[CH:6][C:5]([Cl:4])=[CH:14]2

Participants

5

Reactant 2

HCID 10942334Sodium MethoxideHCID 13090787HCID 13090787, compound

Product 1

HCID 54496620HCID 54496620, compound

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 887MethanolSolvent

Procedure

18 ml of a 15% strength solution of sodium methylate in methanol were added dropwise, at room temperature, to a suspension of 25.4 g of 3,7-dichloro-8-triphenylphosphoniummethylquinoline chloride and 11.3 g of 3,7-dichloro-8-formylquinoline in 150 ml of ethanol. The mixture was stirred for 2 hours, after which the yellow precipitate was filtered off under suction, treated with water and again filtered off under suction.

Workup

  1. filtrationafter which the yellow precipitate was filtered off under suction
  2. additiontreated with water
  3. filtrationagain filtered off under suction

Sources & evidence

ORD record
ord-8841b6b409c7485da9c83fc3053ea8a7
Source dataset
uspto-grants-1988_01
Patent number
US04717416

Reaction notes

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