Water → HCID 136399308, compound

HRID 2413454Notes

Reaction equation

HRID 2413454 reaction equation
[Cl:1][C:2]1[CH:3]=[N:4][C:5]2[C:10]([CH:11]=1)=[CH:9][CH:8]=[C:7]([Cl:12])[C:6]=2C=O.C(=O)([O-])[O-].[Na+].[Na+].[Cl-].[OH:22][NH3+:23].O>C(O)C>[Cl:1][C:2]1[CH:3]=[N:4][C:5]2[C:6](=[N:23][OH:22])[CH:7]([Cl:12])[CH:8]=[CH:9][C:10]=2[CH:11]=1

Participants

6

Reactant 4

HCID 962WaterHCID 10340Sodium CarbonateHCID 21645Hydroxylamine HClHCID 13090787HCID 13090787, compound

Product 1

HCID 136399308HCID 136399308, compoundYield 101.1%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

22.6 g of 3,7-dichloroquinoline-8-carbaldehyde were dissolved in 300 parts of ethanol, 10.6 g of sodium carbonate and 6.9 g of hydroxylammonium chloride were added to this solution, and the suspension was refluxed for 1 hour. Thereafter, 1,000 g of water were added, and the precipitated solid was filtered off and dried to give 23 g (96% of theory) of 3,7-dichloro-8-hydroxyliminoquinoline of melting point 202° C.

Workup

  1. additionwere added to this solution
  2. temperaturethe suspension was refluxed for 1 hour
  3. filtrationthe precipitated solid was filtered off
  4. customdried

Sources & evidence

ORD record
ord-857e5e5224f84b68924b78c77009ccbf
Source dataset
uspto-grants-1988_01
Patent number
US04717416

Reaction notes

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