6-Chrysenecarbaldehyde → 12-Ethoxychrysene-6-carbaldehyde

HRID 2413565노트

반응식

HRID 2413565 반응식
[CH2:1]([O:3][C:4]1[CH:5]=[C:6]2[C:15](=[C:16]3[C:21]=1[CH:20]=[CH:19][CH:18]=[CH:17]3)[CH:14]=[CH:13][C:12]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]2=1)[CH3:2].C1C2C=CC3C(=CC([CH:40]=[O:41])=C4C=3C=CC=C4)C=2C=CC=1>C(Cl)Cl>[CH2:1]([O:3][C:4]1[C:21]2[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=2[C:15]2[C:6](=[C:7]3[C:12](=[C:13]([CH:40]=[O:41])[CH:14]=2)[CH:11]=[CH:10][CH:9]=[CH:8]3)[CH:5]=1)[CH3:2]

참가 물질

4

반응물 2

HCID 124387746-ChrysenecarbaldehydeHCID 144233156-Ethoxychrysene

생성물 1

HCID 1337539112-Ethoxychrysene-6-carbaldehyde수율 64%

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

6-Ethoxychrysene (Cambridge Chemical, Inc., 48 g, 0.176 mol) was formylated according to the procedure outlined in 1A, except that CH2Cl2 (1 L) was used as the reaction solvent. After isolation, the crude material was chromatographed on a plug of SiO2 (500 g) using CH2Cl2 as the eluting solvent to give (after removal of solvent and drying) 33.7 g (64%) of 12-ethoxychrysene-6-carbaldehyde mp 173.5°-176°, (C, H).

후처리

  1. customAfter isolation, the crude material was chromatographed on a plug of SiO2 (500 g)

출처 및 근거

ORD 기록
ord-5ef4edb3a6af4ca09e725b03ee3ba91d
출처 데이터셋
uspto-grants-1988_01
특허 번호
US04719046

반응 노트

불러오는 중…