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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2413579Generated: October 25, 2026

Tris(hydroxymethyl)aminomethane → 2-((6-Chrysenylmethyl)amino)-2-hydroxymethyl-1,3-propanediol hydrochloride

https://huagongshe.com/reaction/2413579

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTris(hydroxymethyl)aminomethaneHCID 6503—
Reactant6-ChrysenecarbaldehydeHCID 12438774—
Reactant2-((6-Chrysenylmethyl)amino)-2-methyl-1,3-propanediol hydrochlorideHCID 13375278—
SolventDiethyl ether methanolHCID 21864698—
Product2-((6-Chrysenylmethyl)amino)-2-hydroxymethyl-1,3-propanediol hydrochlorideHCID 13375340—

Reaction Steps

Using the reactive amination procedure described in 1B, 6-chrysenecarbaldehyde (1A) and tris(hydroxymethyl)aminomethane (Aldrich) gave 2-((6-chrysenylmethyl)amino)-2-hydroxymethyl-1,3-propanediol hydrochloride, mp 238°-239° (dec), (CH3OH/Et2O), (C,H,Cl,N).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04719048
Source datasetuspto-grants-1988_01
ORD IDord-78cacd0e10e449ff9ac19f00fdf68a41
Source noteuspto-grants-1988_01