2-Amino-2-ethyl-1,3-propanediol → HCID 13375299, compound

HRID 2413632Notes

Reaction equation

HRID 2413632 reaction equation
[Cl:1][C:2]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[C:9]([CH:16]=O)=[C:8]2[C:3]=1[CH:4]=[CH:5][CH:6]=[CH:7]2.[NH2:18][C:19]([CH2:24][CH3:25])([CH2:22][OH:23])[CH2:20][OH:21]>CO.CCOCC>[ClH:1].[Cl:1][C:2]1[C:3]2[C:8](=[CH:7][CH:6]=[CH:5][CH:4]=2)[C:9]([CH2:16][NH:18][C:19]([CH2:24][CH3:25])([CH2:22][OH:23])[CH2:20][OH:21])=[C:10]2[C:15]=1[CH:14]=[CH:13][CH:12]=[CH:11]2

Participants

4

Reactant 2

HCID 82822-Amino-2-ethyl-1,3-propanediolHCID 8270310-Chloro-9-anthraldehyde

Product 1

HCID 13375299HCID 13375299, compound

Reagents, catalysts & solvents 1

HCID 21864698Diethyl ether methanolSolvent

Procedure

Using the reductive amination outlined in 1, 10-chloro-9-anthraldehyde (Aldrich) and 2-amino-2-ethyl-1,3-propanediol (Aldrich) gave 2-(((10-chloro-9-anthracenyl)methyl)amino)-2-ethyl-1,3-propanediol hydrochloride, mp 252°-254° (dec), (CH3OH/Et2O), (C, H, Cl, N).

Sources & evidence

ORD record
ord-b3742ac6e1f84f72bb6abdfe94d87675
Source dataset
uspto-grants-1988_01
Patent number
US04719049

Reaction notes

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