HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-2-methyl-1,3-propanediol → 2-(((4-Chloro-10-(2-hydroxyethoxy)-9-anthracenyl)methyl)amino)-2-methyl-1,3-propanediol methanesulfonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-2-methyl-1,3-propanediol | HCID 1531 | — |
| Reactant | 4-Chloro-10-(2-hydroxyethoxy)-9-antracenecarbaldehyde | HCID 14391242 | — |
| Reactant | ((10-Chloro9-anthracenyl)methyl)amino-2-methyl-1,3-propanediol methanesulfonate | HCID 86741972 | — |
| Product | 2-(((4-Chloro-10-(2-hydroxyethoxy)-9-anthracenyl)methyl)amino)-2-methyl-1,3-propanediol methanesulfonate | HCID 21276250 | — |
Reaction Steps
Using the reductive amination procedure outlined in 2B, 4-chloro-10-(2-hydroxyethoxy)-9-anthracenecarbaldehyde (38A) and 2-amino-2-methyl-1,3-propanediol (Aldrich) gave 2-(((4-chloro-10-(2-hydroxyethoxy)-9-anthracenyl)methyl)amino)-2-methyl-1,3-propanediol methanesulfonate. 3/10H2O.1/10i-PrOH mp 156°-158° (dec), (i-PrOH/Et2O), (C, H, Cl, N, S)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04719049 |
| Source dataset | uspto-grants-1988_01 |
| ORD ID | ord-70426e7f59bc4a828c850079b1a1f15d |
| Source note | uspto-grants-1988_01 |