(+-)(2R*,3S*)-2-Methyl-2-nitro-1,3-butanediol → (+-)(2R*,3S*)-2-amino-2-methyl-1,3-butanediol acetate

HRID 2413683Notes

Reaction equation

HRID 2413683 reaction equation
[CH3:1][C@:2]([N+:8]([O-])=O)([C@@H:5]([OH:7])[CH3:6])[CH2:3][OH:4].[C:11]([OH:14])(=[O:13])[CH3:12].N[C@@](C)([C@H](O)C)CO>>[C:11]([OH:14])(=[O:13])[CH3:12].[NH2:8][C@@:2]([CH3:1])([C@@H:5]([OH:7])[CH3:6])[CH2:3][OH:4]

Participants

3

Reactant 2

HCID 13375424(+-)(2R*,3S*)-2-Methyl-2-nitro-1,3-butanediolHCID 86741969(+-)(2R*,3R*)-2-amino-2-methyl-1,3-butanediol acetate

Product 1

HCID 86741966(+-)(2R*,3S*)-2-amino-2-methyl-1,3-butanediol acetate

Procedure

Prepared from (+-)(2R*,3S*)-2-methyl-2-nitro-1,3-butanediol (7A) as described for 7E (93%) (C,H,N) mp 163°-165° C.

Sources & evidence

ORD record
ord-37dc2dc1b2e24d5ba029b3233f0db129
Source dataset
uspto-grants-1988_01
Patent number
US04719055

Reaction notes

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