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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2413685Generated: October 26, 2026

Phenanthrene-9-carbaldehyde → 3-Methoxy-2-methyl-2-((9-phenanthrenylmethyl)amino)-1-propanol hydrochloride

https://huagongshe.com/reaction/2413685

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenanthrene-9-carbaldehydeHCID 78437—
Reactant2-Amino-3-methoxy-2-methylpropan-1-olHCID 13375415—
Reactant(+-)(2R*,3S*)-2-((9-Phenanthrenylmethyl)amino)-2-methyl-1,3-butanediol hydrochlorideHCID 86741971—
Product3-Methoxy-2-methyl-2-((9-phenanthrenylmethyl)amino)-1-propanol hydrochlorideHCID 21273677—

Reaction Steps

Using the reductive amination procedure outlined in 7G, phenanthrene-9-carbaldehyde (Aldrich) and 2-amino-3-methoxy-2-methyl-1-propanol (9C) gave 3-methoxy-2-methyl-2-((9-phenanthrenylmethyl)amino)-1-propanol hydrochloride mp 211°-213° (dec), (EtOH/Et2O), (C,H,Cl,N).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04719055
Source datasetuspto-grants-1988_01
ORD IDord-77f712a0a406492383a8c1b9d55c933b
Source noteuspto-grants-1988_01