HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 3-(4-acetyl-2-methylphenyl)acrylate → Methyl 3-[2-methyl-4-[3-[3-propyl-6-(trifluoromethyl)benzothiophen-2-yl]propenoyl]phenyl]acrylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 3-(4-acetyl-2-methylphenyl)acrylate | HCID 66883900 | — |
| Reactant | 3-Propyl-6-(trifluoromethyl)benzothiophene-2-carboxaldehyde | HCID 86652864 | — |
| Product | Methyl 3-[2-methyl-4-[3-[3-propyl-6-(trifluoromethyl)benzothiophen-2-yl]propenoyl]phenyl]acrylate | HCID 66883222 | — |
Reaction Steps
The titled compound was prepared from the above-mentioned 3-propyl-6-(trifluoromethyl)benzothiophen-2-carboxaldehyde (112 mg, 0.411 mmol) and methyl 3-(4-acetyl-2-methylphenyl)acrylate (90 mg, 0.41 mmol) in a procedure similar to that of Example 7 (1) as a yellow crystal (107 mg, yield 55%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08648208B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-dec5b01e56084155910184cb807af82c |
| Source note | uspto-grants-2014_02 |