HuagongsheHuagongshe Chemistry Print Report · For research reference only
[3-Propyl-6-(trifluoromethyl)-benzothiophen-2-yl]methanol → 3-[2-Methyl-4-[3-[3-propyl-6-(trifluoromethyl)benzothiophen-2-yl]propionyl]phenyl]propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | [3-Propyl-6-(trifluoromethyl)-benzothiophen-2-yl]methanol | HCID 66883667 | — |
| Reactant | Methyl 3-[2-methyl-4-[3-[3-propyl-6-(trifluoromethyl)benzothiophen-2-yl]propionyl]phenyl]propionate | HCID 66883766 | — |
| Product | 3-[2-Methyl-4-[3-[3-propyl-6-(trifluoromethyl)benzothiophen-2-yl]propionyl]phenyl]propionic acid | HCID 44466764 | — |
Reaction Steps
The titled compound was prepared from the above-mentioned methyl 3-[2-methyl-4-[3-[3-propyl-6-(trifluoromethyl)benzothiophen-2-yl]propionyl]phenyl]propionate (38 mg, 0.08 mmol) in a procedure similar to that of Example (3) as a white crystal (14 mg, yield 66%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08648208B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-8b336d26077b43d69588305524011ba5 |
| Source note | uspto-grants-2014_02 |