N-[(Benzyloxy)carbonyl]-L-alanyl-L-prolyl-L-proline → HCID 178462186, compound

HRID 2413730Notes

Reaction equation

HRID 2413730 reaction equation
[CH2:1]([O:8][C:9]([NH:11][C@H:12]([C:14]([N:16]1[CH2:30][CH2:29][CH2:28][C@H:17]1[C:18]([N:20]1[CH2:27][CH2:26][CH2:25][C@H:21]1[C:22]([OH:24])=[O:23])=[O:19])=[O:15])[CH3:13])=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH2:31][C@H:32]([C:40]([OH:42])=[O:41])[CH2:33][CH2:34][CH2:35][NH:36][C:37](=[NH:39])[NH2:38]>O>[NH2:31][C@H:32]([C:40]([OH:42])=[O:41])[CH2:33][CH2:34][CH2:35][NH:36][C:37](=[NH:38])[NH2:39].[CH2:1]([O:8][C:9]([NH:11][C@H:12]([C:14]([N:16]1[CH2:30][CH2:29][CH2:28][C@H:17]1[C:18]([N:20]1[CH2:27][CH2:26][CH2:25][C@H:21]1[C:22]([OH:24])=[O:23])=[O:19])=[O:15])[CH3:13])=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 18611257N-[(Benzyloxy)carbonyl]-L-alanyl-L-prolyl-L-prolineHCID 178418600HCID 178418600, compound

Product 1

HCID 178462186HCID 178462186, compoundYield 98.8%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

N-benzyloxycarbonyl-L-alanyl-L-prolyl-L-proline (1.00 g, 2.40 m mole) was dissolved in L-arginine (0.41 8 g, 2.40 m mole) - water (50 ml) solution and the thus obtained solution was freeze-dried to obtain N-benzyloxycarbonyl-L-alanyl-L-prolyl-L-proline L -arginine salt (1.40 g).

Workup

  1. customthe thus obtained solution was freeze-dried

Sources & evidence

ORD record
ord-a9bc80f7a5864af4839a6cd8cc845595
Source dataset
uspto-grants-1988_01
Patent number
US04719200

Reaction notes

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