Ethyl formate → HCID 13983427, compound

Participants

Reaction Steps

The procedure is analogous to that described in Example 11, but starting with sodium (2.3 g), 3-methoxyacetophenone (15 g) and ethyl formate (11 g). The solid obtained (20 g) is then added to 2,6-diaminopyridine (11 g). The product obtained after hydrolysis and neutralization with sodium hydroxide is separated by filtration, washed with distilled water (6×100 cc) at 50° C., and then air-dried. 2-Amino-7-(3-methoxyphenyl)-1,8-naphthyridine (23.8 g), m.p. 270°-275° C., is obtained.

Provenance & Evidence