Sodium Hydroxide → HCID 19838107, compound

Participants

Reaction Steps

The product of step (c) (6 g., 14.6 mmoles) and lithium aluminium hydride (1 M solution in ether, 60 ml, 60 mmoles) in dry dichloromethane (200 ml) were heated at reflux under nitrogen for 5 hrs. The suspension was cooled and poured slowly into an ice-cold 10% aqueous solution of sodium hydroxide. The organic phase was separated, washed with brine and evaporated. Recrystallisation of the residue from 2-propanol afforded the sub-title compound (2.0 g) mp 270°-272°.

Provenance & Evidence