beta3,beta3,beta9,beta9-Tetramethyl-2,4,8,10-tetraoxaspiro(5.5)undecane-3,9-diethanol → 3,9-Bis[2-[3-(3-tert-butyl-4-hydroxy-5-isopropylphenyl)propionyloxy]-1,1-dimethylethyl]-2,4,8,10-tetraoxaspiro[5.5]undecane

Participants

Reaction Steps

Using a mixture of 33.6 g (0.121 mole) of methyl 3-(3-tertbutyl-4-hydroxy-5-isopropylphenyl)propionate, 15.3 g (0.0503 mole) of 3,9-bis(2-hydroxy-1,1-dimethylethyl)-2,4,8,10-tetraoxaspiro[5.5]-undecane and 0.82 g (0.015 mole) of sodium methoxide, reaction; after-treatment and purification were carried out in the same manner as in Preparation example 1 to obtain 29 g of 98%-purity 3,9-bis[2-[3-(3-tert-butyl-4-hydroxy-5-isopropylphenyl)propionyloxy]-1,1-dimethylethyl]-2,4,8,10-tetraoxaspiro[5.5]undecane as a colorless glassy product (Compound I-2). m.p., 47°-57° C.

Provenance & Evidence