Hydrochloric Acid → HCID 14151573, compound

Participants

Reaction Steps

A mixture of 40 g of 6-(4-methoxyphenoxy)-1-phthalimido-4-hexynylamine and 8.5 g of N,N-diethylaniline in 400 ml of N-methylpyrrolidinone is heated at 210° for 30 hours. After pouring onto water containing 57 ml of 1N hydrochloric acid the product is extracted with ether, dried, and the solvent is removed in vacuo. The residue is crystallized from isopropyl alcohol to afford 4-(3-phthalimidopropyl)-6-methoxy-2H-[1]-benzopyran, melting point 78°-80°.

Provenance & Evidence